Detection of Human Papillomavirus (HPV) DNA in Cord Blood of Newborns in Ilorin, Nigeria
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Abstract
The contagious virus known as the human papillomavirus (HPV) can proliferate within live cells. The virus has icosahedral symmetry and is small. It has a diameter of 50–60 nm. Its double-stranded, closed circular DNA genome is protected by a capsid made up of two late proteins (L1 and L2), and it is a member of the Papillomaviridae family. The most prevalent viral sexually transmitted infection in humans, the human papillomavirus, is known to cause malignancies of the head, neck, anogenital area, and cervical region. At the University of Ilorin Teaching Hospital's prenatal clinic, 113 expectant women were examined. For molecular detection, DNA extraction, and HP-viral screening, MY09/MY11 and GP5+/GP6+ consensus primers were employed. HP-viral DNA was found in 54 (47.8%) of the cord blood samples. Infants' HPV DNA may indicate HPV-related diseases. To avoid transmission during pregnancy, routine monitoring and surveillance are advised for both pregnant and postpartum women, and HPV vaccination is required during family planning before pregnancy.
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References
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